产品货号：
Z31454
中文名称：
ELA2/ELANE抗体
英文名称：
Anti-ELA2/ELANE Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ELA2/ELANE Antibody |
| 指标别名 | Bone marrow serine protease;ELA2;ELANE;Elastase 2;elastase 2;neutrophil;GE;HLE;HNE;Human leukocyte elastase;Medullasin;NE;Neutrophil elastase;PMN E;PMN elastase |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | ELANE |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Neutrophil Elastase |
| 实际分子量 | 29KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Neutrophil elastase is a serine protease of neutrophil and monocyte granules.Its key physiologic role is in innate host defense,but it can also participate in tissue remodeling and possesses secretagogue actions important to local inflammatory responses.Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin.Humans have six elastase genes which encode structurally similar proteins.The encoded preproprotein is proteolytically processed to generate the active protease.Following activation,this protease hydrolyzes proteins within specialized neutrophil lysosomes,called azurophil granules,as well as proteins of the extracellular matrix.This protein also degrades the outer membrane protein A (OmpA) of E.coli as well as the virulence factors of such bacteria as Shigella,Salmonella and Yersinia.Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN).This gene is present in a gene cluster on chromosome 19. |
| Uniprot ID | P08246 |
| 基因名全称 | Neutrophil elastase |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
相关搜索：ELA2/ELANE抗体，ELA2抗体，ELANE单抗，Anti-ELA2/ELANE Antibody